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Sensitivity of non-small cell lung cancer to erlotinib is regulated by the Notch/miR-223/FBXW7 pathway

Recent evidence supports a role for microRNA-223 (miR-223) in modulating tumor cell sensitivity to chemotherapeutic drugs; however, its role in cellular resistance to the effects of epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) used in treatment of non-small cell lung cance...

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Detalles Bibliográficos
Autores principales: Zhang, Haiwei, Chen, Fanglin, He, Yongpeng, Yi, Lin, Ge, Chuang, Shi, Xiaolong, Tang, Chao, Wang, Donglin, Wu, Yongzhong, Nian, Weiqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5479025/
https://www.ncbi.nlm.nih.gov/pubmed/28507201
http://dx.doi.org/10.1042/BSR20160478