Cargando…
Sensitivity of non-small cell lung cancer to erlotinib is regulated by the Notch/miR-223/FBXW7 pathway
Recent evidence supports a role for microRNA-223 (miR-223) in modulating tumor cell sensitivity to chemotherapeutic drugs; however, its role in cellular resistance to the effects of epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) used in treatment of non-small cell lung cance...
Autores principales: | Zhang, Haiwei, Chen, Fanglin, He, Yongpeng, Yi, Lin, Ge, Chuang, Shi, Xiaolong, Tang, Chao, Wang, Donglin, Wu, Yongzhong, Nian, Weiqi |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5479025/ https://www.ncbi.nlm.nih.gov/pubmed/28507201 http://dx.doi.org/10.1042/BSR20160478 |
Ejemplares similares
-
miR-223 functions as a potent tumor suppressor of the Lewis lung carcinoma cell line by targeting insulin-like growth factor-1 receptor and cyclin-dependent kinase 2
por: NIAN, WEIQI, et al.
Publicado: (2013) -
MiR-223 promotes oral squamous cell carcinoma proliferation and migration by regulating FBXW7
por: Jiang, Lihua, et al.
Publicado: (2019) -
HnRNPK/miR-223/FBXW7 feedback cascade promotes pancreatic cancer cell growth and invasion
por: He, De, et al.
Publicado: (2017) -
miR‐223‐3p targets FBXW7 to promote epithelial‐mesenchymal transition and metastasis in breast cancer
por: Wang, Yuli, et al.
Publicado: (2021) -
MiR-223-3p affects myocardial inflammation and apoptosis following myocardial infarction via targeting FBXW7
por: Zhang, Libin, et al.
Publicado: (2022)