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A new monoclonal antibody detects downregulation of protein tyrosine phosphatase receptor type γ in chronic myeloid leukemia patients

BACKGROUND: Protein tyrosine phosphatase receptor gamma (PTPRG) is a ubiquitously expressed member of the protein tyrosine phosphatase family known to act as a tumor suppressor gene in many different neoplasms with mechanisms of inactivation including mutations and methylation of CpG islands in the...

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Detalles Bibliográficos
Autores principales: Vezzalini, Marzia, Mafficini, Andrea, Tomasello, Luisa, Lorenzetto, Erika, Moratti, Elisabetta, Fiorini, Zeno, Holyoake, Tessa L., Pellicano, Francesca, Krampera, Mauro, Tecchio, Cristina, Yassin, Mohamed, Al-Dewik, Nader, Ismail, Mohamed A., Al Sayab, Ali, Monne, Maria, Sorio, Claudio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5479035/
https://www.ncbi.nlm.nih.gov/pubmed/28637510
http://dx.doi.org/10.1186/s13045-017-0494-z