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Osteopontin is Critical for Hyperactive mTOR-Induced Tumorigenesis in Oral Squamous Cell Carcinoma

Mechanistic target of rapamycin (mTOR) plays a critical role in the development of oral squamous cell carcinoma (OSCC), but the underlying mechanisms remain poorly understood. Here we have demonstrated that the expression of osteopontin (OPN) was dramatically up-regulated in OSCC tissues and cell li...

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Detalles Bibliográficos
Autores principales: Gan, Ning, Zou, Sihai, Hang, Wenming, Yang, Deqin, Zhang, Xuemei, Yin, Yibing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5479241/
https://www.ncbi.nlm.nih.gov/pubmed/28638450
http://dx.doi.org/10.7150/jca.18031