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ZEB1 Mediates Drug Resistance and EMT in p300-Deficient CRC

We discuss the hypothesis that ZEB1-Wnt-p300 signaling integrates epithelial to mesenchymal transition (EMT) and resistance to histone deacetylase inhibitors (HDACis) in colorectal cancer (CRC) cells. The HDACi butyrate, derived from dietary fiber, has been linked to CRC prevention, and other HDACis...

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Detalles Bibliográficos
Autores principales: Lazarova, Darina, Bordonaro, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5479251/
https://www.ncbi.nlm.nih.gov/pubmed/28638460
http://dx.doi.org/10.7150/jca.18762