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Overexpression of PAK1 Correlates with Aberrant Expression of EMT Markers and Poor Prognosis in Non-Small Cell Lung Cancer

Objective: p21-activated kinases (PAKs) are serine/threonine protein kinases. PAK1 and epithelial-mesenchymal transition (EMT) are key therapeutic targets in cancer. The clinical significance of PAK1 and its potential association with EMT phenotype in non-small cell lung cancer (NSCLC) was investiga...

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Detalles Bibliográficos
Autores principales: Yang, Zhiying, Wang, Heran, Xia, Longzheng, Oyang, Linda, Zhou, Yujuan, Zhang, Baihua, Chen, Xiaoyan, Luo, Xia, Liao, Qianjin, Liang, Jianping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5479255/
https://www.ncbi.nlm.nih.gov/pubmed/28638464
http://dx.doi.org/10.7150/jca.18553