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Tamoxifen activates Nrf2-dependent SQSTM1 transcription to promote endometrial hyperplasia

Long-term application of Tamoxifen (TAM) is usually recommended for hormone receptor positive breast cancer patients. Unfortunately, TAM will inevitably increase the incidence of endometrial hyperplasia even endometrial cancer. Despite of substantial investigations, no effective approaches to preven...

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Detalles Bibliográficos
Autores principales: Feng, Lifeng, Li, Jiaqiu, Yang, Lixian, Zhu, Libo, Huang, Xiufeng, Zhang, Shuzheng, Luo, Likang, Jiang, Zhinong, Jiang, Tingting, Xu, Wenxia, Wang, Xian, Jin, Hongchuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5479276/
https://www.ncbi.nlm.nih.gov/pubmed/28638475
http://dx.doi.org/10.7150/thno.19135