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Tamoxifen activates Nrf2-dependent SQSTM1 transcription to promote endometrial hyperplasia
Long-term application of Tamoxifen (TAM) is usually recommended for hormone receptor positive breast cancer patients. Unfortunately, TAM will inevitably increase the incidence of endometrial hyperplasia even endometrial cancer. Despite of substantial investigations, no effective approaches to preven...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5479276/ https://www.ncbi.nlm.nih.gov/pubmed/28638475 http://dx.doi.org/10.7150/thno.19135 |