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Triptolide Inhibits the AR Signaling Pathway to Suppress the Proliferation of Enzalutamide Resistant Prostate Cancer Cells

Enzalutamide is a second-generation androgen receptor (AR) antagonist for the treatment of metastatic castration-resistant prostate cancer (mCRPC). Unfortunately, AR dysfunction means that resistance to enzalutamide will eventually develop. Thus, novel agents are urgently needed to treat this devast...

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Detalles Bibliográficos
Autores principales: Han, Yangyang, Huang, Weiwei, Liu, Jiakuan, Liu, Dandan, Cui, Yangyan, Huang, Ruimin, Yan, Jun, Lei, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5479278/
https://www.ncbi.nlm.nih.gov/pubmed/28638477
http://dx.doi.org/10.7150/thno.17852