Cryptotanshinone induces cell cycle arrest and apoptosis through the JAK2/STAT3 and PI3K/Akt/NFκB pathways in cholangiocarcinoma cells

BACKGROUND: Cholangiocarcinoma (CCA) is the most common biliary tract malignancy in the world with high resistance to current chemotherapies and extremely poor prognosis. The main objective of this study was to investigate the inhibitory effects of cryptotanshinone (CTS), a natural compound isolated...

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Detalles Bibliográficos
Autores principales: Ke, Fayong, Wang, Zheng, Song, Xiaoling, Ma, Qiang, Hu, Yunping, Jiang, Lin, Zhang, Yijian, Liu, Yingbin, Zhang, Yong, Gong, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5479302/
https://www.ncbi.nlm.nih.gov/pubmed/28670110
http://dx.doi.org/10.2147/DDDT.S132488

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5479302/
https://www.ncbi.nlm.nih.gov/pubmed/28670110
http://dx.doi.org/10.2147/DDDT.S132488

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