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Hippocampal overexpression of Down syndrome cell adhesion molecule in amyloid precursor protein transgenic mice

Down syndrome cell adhesion molecule (DSCAM) is located within the Down syndrome critical region of chromosome 21. DSCAM is a broadly expressed neurodevelopmental protein involved in synaptogenesis, neurite outgrowth, and axon guidance. We previously demonstrated DSCAM overexpression in the cortex o...

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Detalles Bibliográficos
Autores principales: Jia, Y.L., Fu, Z.X., Zhang, B.H., Jia, Y.J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Associação Brasileira de Divulgação Científica 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5479388/
https://www.ncbi.nlm.nih.gov/pubmed/28513774
http://dx.doi.org/10.1590/1414-431X20176049