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Intracellular delivery of biologic therapeutics by bacterial secretion systems
Biologics are a promising new class of drugs based on complex macromolecules such as proteins and nucleic acids. However, delivery of these macromolecules into the cytoplasm of target cells remains a significant challenge. Here we present one potential solution: bacterial nanomachines that have evol...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cambridge University Press
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5479498/ https://www.ncbi.nlm.nih.gov/pubmed/28382885 http://dx.doi.org/10.1017/erm.2017.7 |