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The Ebola virus VP35 protein binds viral immunostimulatory and host RNAs identified through deep sequencing

Ebola virus and Marburg virus are members of the Filovirdae family and causative agents of hemorrhagic fever with high fatality rates in humans. Filovirus virulence is partially attributed to the VP35 protein, a well-characterized inhibitor of the RIG-I-like receptor pathway that triggers the antivi...

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Detalles Bibliográficos
Autores principales: Dilley, Kari A., Voorhies, Alexander A., Luthra, Priya, Puri, Vinita, Stockwell, Timothy B., Lorenzi, Hernan, Basler, Christopher F., Shabman, Reed S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5479518/
https://www.ncbi.nlm.nih.gov/pubmed/28636653
http://dx.doi.org/10.1371/journal.pone.0178717