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SensiScreen(®) KRAS exon 2-sensitive simplex and multiplex real-time PCR-based assays for detection of KRAS exon 2 mutations

Activating mutations in codon 12 and codon 13 of the KRAS (Kirsten rat sarcoma viral oncogene homolog) gene are implicated in the development of several human cancer types and influence their clinical evaluation, treatment and prognosis. Numerous different methods for KRAS genotyping are currently a...

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Detalles Bibliográficos
Autores principales: Riva, Alice, BØrgesen, Michael, Guldmann-Christensen, Mariann, Hauge Kyneb, Majbritt, Voogd, Kirsten, Andersen, Christina, Epistolio, Samantha, Merlo, Elisabetta, Yding Wolff, Tine, Hamilton-Dutoit, Stephen, Lorenzen, Jan, Christensen, Ulf Bech, Frattini, Milo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5479524/
https://www.ncbi.nlm.nih.gov/pubmed/28636636
http://dx.doi.org/10.1371/journal.pone.0178027