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Selective propagation of mouse-passaged scrapie prions with long incubation period from a mixed prion population using GT1-7 cells
In our previous study, we demonstrated the propagation of mouse-passaged scrapie isolates with long incubation periods (L-type) derived from natural Japanese sheep scrapie cases in murine hypothalamic GT1-7 cells, along with disease-associated prion protein (PrP(Sc)) accumulation. We here analyzed t...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5479544/ https://www.ncbi.nlm.nih.gov/pubmed/28636656 http://dx.doi.org/10.1371/journal.pone.0179317 |