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MicroRNA-144-3p inhibits autophagy activation and enhances Bacillus Calmette-Guérin infection by targeting ATG4a in RAW264.7 macrophage cells

MicroRNAs (miRNAs) are small noncoding nucleotides that play major roles in the response of host immune cells. Autophagy plays a key role in activating the antimicrobial host defense against Mycobacterium tuberculosis (M. tuberculosis). Whether miRNAs specifically influence the activation of macroph...

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Detalles Bibliográficos
Autores principales: Guo, Le, Zhou, Linlin, Gao, Qian, Zhang, Aijun, Wei, Jun, Hong, Dantong, Chu, Yuankui, Duan, Xiangguo, Zhang, Ying, Xu, Guangxian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5479589/
https://www.ncbi.nlm.nih.gov/pubmed/28636635
http://dx.doi.org/10.1371/journal.pone.0179772