Serotonin rebalances cortical tuning and behavior linked to autism symptoms in 15q11-13 CNV mice

Serotonin is a critical modulator of cortical function, and its metabolism is defective in autism spectrum disorder (ASD) brain. How serotonin metabolism regulates cortical physiology and contributes to the pathological and behavioral symptoms of ASD remains unknown. We show that normal serotonin le...

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Detalles Bibliográficos
Autores principales: Nakai, Nobuhiro, Nagano, Masatoshi, Saitow, Fumihito, Watanabe, Yasuhito, Kawamura, Yoshinobu, Kawamoto, Akiko, Tamada, Kota, Mizuma, Hiroshi, Onoe, Hirotaka, Watanabe, Yasuyoshi, Monai, Hiromu, Hirase, Hajime, Nakatani, Jin, Inagaki, Hirofumi, Kawada, Tomoyuki, Miyazaki, Taisuke, Watanabe, Masahiko, Sato, Yuka, Okabe, Shigeo, Kitamura, Kazuo, Kano, Masanobu, Hashimoto, Kouichi, Suzuki, Hidenori, Takumi, Toru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5479676/
https://www.ncbi.nlm.nih.gov/pubmed/28691086
http://dx.doi.org/10.1126/sciadv.1603001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5479676/
https://www.ncbi.nlm.nih.gov/pubmed/28691086
http://dx.doi.org/10.1126/sciadv.1603001

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