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Treatment of sarcopenia and glucose intolerance through mitochondrial activation by 5-aminolevulinic acid

Recently, sarcopenia has attracted attention as therapeutic target because it constitutes a risk factor for metabolic and cardiovascular diseases. We focused 5-aminolevulinic acid (ALA) which act as electron carriers in the mitochondrial electron transport system. The mice that received ALA for 8 we...

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Detalles Bibliográficos
Autores principales: Fujii, Chikako, Miyashita, Kazutoshi, Mitsuishi, Masanori, Sato, Masaaki, Fujii, Kentaro, Inoue, Hiroyuki, Hagiwara, Aika, Endo, Sho, Uto, Asuka, Ryuzaki, Masaki, Nakajima, Motowo, Tanaka, Tohru, Tamaki, Masanori, Muraki, Ayako, Kawai, Toshihide, Itoh, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5479778/
https://www.ncbi.nlm.nih.gov/pubmed/28638045
http://dx.doi.org/10.1038/s41598-017-03917-0