Cargando…

Treatment of sarcopenia and glucose intolerance through mitochondrial activation by 5-aminolevulinic acid

Recently, sarcopenia has attracted attention as therapeutic target because it constitutes a risk factor for metabolic and cardiovascular diseases. We focused 5-aminolevulinic acid (ALA) which act as electron carriers in the mitochondrial electron transport system. The mice that received ALA for 8 we...

Descripción completa

Detalles Bibliográficos
Autores principales:	Fujii, Chikako, Miyashita, Kazutoshi, Mitsuishi, Masanori, Sato, Masaaki, Fujii, Kentaro, Inoue, Hiroyuki, Hagiwara, Aika, Endo, Sho, Uto, Asuka, Ryuzaki, Masaki, Nakajima, Motowo, Tanaka, Tohru, Tamaki, Masanori, Muraki, Ayako, Kawai, Toshihide, Itoh, Hiroshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5479778/ https://www.ncbi.nlm.nih.gov/pubmed/28638045 http://dx.doi.org/10.1038/s41598-017-03917-0

Ejemplares similares

Angiotensin II Reduces Mitochondrial Content in Skeletal Muscle and Affects Glycemic Control
por: Mitsuishi, Masanori, et al.
Publicado: (2009)

Transient Dexamethasone Loading Induces Prolonged Hyperglycemia in Male Mice With Histone Acetylation in Dpp-4 Promoter
por: Uto, Asuka, et al.
Publicado: (2021)

Activation of the intestinal tissue renin-angiotensin system by transient sodium loading in salt-sensitive rats
por: Ryuzaki, Masaki, et al.
Publicado: (2022)

Intermittent Fasting Sustainably Improves Glucose Tolerance in Normal Weight Male Mice Through Histone Hyperacetylation
por: Endo, Sho, et al.
Publicado: (2023)

Combination of 5‐aminolevulinic acid and ferrous ion reduces plasma glucose and hemoglobin A1c levels in Zucker diabetic fatty rats
por: Hara, Takeshi, et al.
Publicado: (2016)

The Effect of 5-Aminolevulinic Acid on Cytochrome P450-Mediated Prodrug Activation
por: Miura, Mai, et al.
Publicado: (2015)

The effects of the heme precursor 5-aminolevulinic acid (ALA) on REV-ERBα activation
por: Yamashita, Kohei, et al.
Publicado: (2014)

The Effect of Iron Ion on the Specificity of Photodynamic Therapy with 5-Aminolevulinic Acid
por: Hayashi, Maiko, et al.
Publicado: (2015)

Safety and Mode of Action of Diabetes Medications in comparison with 5-Aminolevulinic Acid (5-ALA)
por: Rehani, Peter R., et al.
Publicado: (2019)

5-Aminolevulinic acid regulates the immune response in LPS-stimulated RAW 264.7 macrophages
por: Sugiyama, Yuta, et al.
Publicado: (2018)

The effect of 5-aminolevulinic acid on cytochrome c oxidase activity in mouse liver
por: Ogura, Shun-ichiro, et al.
Publicado: (2011)

Effects of 5-aminolevulinic acid and sodium ferrous citrate on fibroblasts from individuals with mitochondrial diseases
por: Shimura, Masaru, et al.
Publicado: (2019)

Efficacy and Safety of 5-Aminolevulinic Acid for Patients with Symptoms of Late-Onset Hypogonadism: A Preliminary Study
por: Koyasu, Hiroki, et al.
Publicado: (2022)

Artesunate Enhances the Cytotoxicity of 5-Aminolevulinic Acid-Based Sonodynamic Therapy against Mouse Mammary Tumor Cells In Vitro
por: Osaki, Tomohiro, et al.
Publicado: (2017)

Quality of life and physical/psychosocial factors in children and adolescents with orthostatic intolerance
por: Shigeyasu, Yoshie, et al.
Publicado: (2023)

A Randomized Phase 2 Study of 5-Aminolevulinic Acid Hydrochloride and Sodium Ferrous Citrate for the Prevention of Nephrotoxicity Induced by Cisplatin-Based Chemotherapy of Lung Cancer
por: Kawamura, Kodai, et al.
Publicado: (2022)

In Vivo Curative and Protective Potential of Orally Administered 5-Aminolevulinic Acid plus Ferrous Ion against Malaria
por: Suzuki, Shigeo, et al.
Publicado: (2015)

Relationships between Composition of Major Fatty Acids and Fat Distribution and Insulin Resistance in Japanese
por: Fujii, Chikako, et al.
Publicado: (2017)

Impact of 5-aminolevulinic acid with iron supplementation on exercise efficiency and home-based walking training achievement in older women
por: Masuki, Shizue, et al.
Publicado: (2015)

Dormant cancer cells accumulate high protoporphyrin IX levels and are sensitive to 5-aminolevulinic acid-based photodynamic therapy
por: Nakayama, Taku, et al.
Publicado: (2016)

The Safety and Tolerability of 5-Aminolevulinic Acid Phosphate with Sodium Ferrous Citrate in Patients with Type 2 Diabetes Mellitus in Bahrain
por: Al-Saber, Feryal, et al.
Publicado: (2016)

5-Aminolevulinic acid with ferrous iron improves early renal damage and hepatic steatosis in high fat diet-induced obese mice
por: Kamiya, Atsuko, et al.
Publicado: (2019)

5-aminolevulinic acid (ALA) deficiency causes impaired glucose tolerance and insulin resistance coincident with an attenuation of mitochondrial function in aged mice
por: Saitoh, Shinichi, et al.
Publicado: (2018)

5-Aminolevulinic Acid Attenuates Atherosclerotic Plaque Progression in Low-Density Lipoprotein Receptor-Deficient Mice by Heme Oxygenase-1 Induction
por: Hagisawa, Kohsuke, et al.
Publicado: (2019)

The Pathogenic and Therapeutic Implications of Ceramide Abnormalities in Atopic Dermatitis
por: Fujii, Masanori
Publicado: (2021)

Acute Interstitial Nephritis With Karyomegalic Epithelial Cells After Nivolumab Treatment—Two Case Reports
por: Ryuzaki, Masaki, et al.
Publicado: (2019)

Relationship between Oral Hypofunction and Sarcopenia in Community-Dwelling Older Adults: The Otassha Study
por: Kugimiya, Yoshihiro, et al.
Publicado: (2021)

Development and evaluation of microsatellite markers for the critically endangered birch Betula chichibuensis (Betulaceae)(1)
por: Igarashi, Yuji, et al.
Publicado: (2017)

Clinical efficacy and safety of combination therapy of tocilizumab and steroid pulse therapy for critical COVID-19 in HD patients
por: Toda, Masataro, et al.
Publicado: (2021)

Suppression of angiotensin converting enzyme 2, a host receptor for SARS-CoV-2 infection, using 5-aminolevulinic acid in vitro
por: Nara, Eriko, et al.
Publicado: (2023)

5-aminolevulinic acid combined with ferrous ion reduces adiposity and improves glucose tolerance in diet-induced obese mice via enhancing mitochondrial function
por: Ota, Urara, et al.
Publicado: (2017)

Adrenal Insufficiency under Standard Dosage of Glucocorticoid Replacement after Unilateral Adrenalectomy for Cushing's Syndrome
por: Fujii, Kentaro, et al.
Publicado: (2016)

Correlation of Expression Levels of Copper Transporter 1 and Thymidylate Synthase with Treatment Outcomes in Patients with Advanced Non-small Cell Lung Cancer Treated with S-1/Carboplatin Doublet Chemotherapy
por: Konishi, Maho, et al.
Publicado: (2018)

Muscle Mass Assessment in Sarcopenia: A Narrative Review
por: Muraki, Isao
Publicado: (2023)

Fluorescent detection of peritoneal metastasis in human colorectal cancer using 5-aminolevulinic acid
por: KONDO, YUTAKA, et al.
Publicado: (2014)

Reduction of fatigue and anger-hostility by the oral administration of 5-aminolevulinic acid phosphate: a randomized, double-blind, placebo-controlled, parallel study
por: Higashikawa, Fumiko, et al.
Publicado: (2020)

Metabolic and Molecular Basis of Sarcopenia: Implications in the Management of Urothelial Carcinoma
por: Fukushima, Hiroshi, et al.
Publicado: (2019)

5‐Aminolevulinic acid/sodium ferrous citrate enhanced the antitumor effects of programmed cell death‐ligand 1 blockade by regulation of exhausted T cell metabolism in a melanoma model
por: Hu, Xin, et al.
Publicado: (2021)

Xanthine Oxidoreductase Inhibitor Use Associated With Reduced Risk of Sarcopenia and Severe Sarcopenia in Patients Undergoing Hemodialysis
por: Kurajoh, Masafumi, et al.
Publicado: (2022)

5-aminolevulinic acid-mediated photodynamic therapy can target aggressive adult T cell leukemia/lymphoma resistant to conventional chemotherapy
por: Sando, Yasuhisa, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_6ivg16aedimbju5m6vauvl7obh