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Wnt2b attenuates HSCs activation and liver fibrosis through negative regulating TLR4 signaling

The Wingless-type MMTV integration site family member 2b (Wnt2b) has been found to be a principal mediator of liver development and regeneration. However, the significance of Wnt2b in the pathogenesis of fibrosis-related liver diseases remains undefined. Here, we report that Wnt2b was highly express...

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Detalles Bibliográficos
Autores principales: Yuan, Yi, Han, Qiuju, Li, Siyu, Tian, Zhigang, Zhang, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5479809/
https://www.ncbi.nlm.nih.gov/pubmed/28638086
http://dx.doi.org/10.1038/s41598-017-04374-5