High efficacy in vitro selection procedure for generating transgenic parasites of Plasmodium berghei using an antibiotic toxic to rodent hosts

The malaria parasite Plasmodium berghei is one of the main rodent malaria models. A shortcoming of this model parasite is its low flexibility in genetic manipulation. As this parasite cannot be continuously propagated in cell cultures, in vivo drug selection procedures are necessary to isolate genet...

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Detalles Bibliográficos
Autores principales: Soga, Akira, Bando, Hironori, Ko-ketsu, Mami, Masuda-Suganuma, Hirono, Kawazu, Shin-ichiro, Fukumoto, Shinya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5479828/
https://www.ncbi.nlm.nih.gov/pubmed/28638105
http://dx.doi.org/10.1038/s41598-017-04244-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5479828/
https://www.ncbi.nlm.nih.gov/pubmed/28638105
http://dx.doi.org/10.1038/s41598-017-04244-0

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