The stress response factor daf-16/FOXO is required for multiple compound families to prolong the function of neurons with Huntington’s disease

Helping neurons to compensate for proteotoxic stress and maintain function over time (neuronal compensation) has therapeutic potential in aging and neurodegenerative disease. The stress response factor FOXO3 is neuroprotective in models of Huntington’s disease (HD), Parkinson’s disease and motor-neu...

Descripción completa

Detalles Bibliográficos
Autores principales: Farina, Francesca, Lambert, Emmanuel, Commeau, Lucie, Lejeune, François-Xavier, Roudier, Nathalie, Fonte, Cosima, Parker, J. Alex, Boddaert, Jacques, Verny, Marc, Baulieu, Etienne-Emile, Neri, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5479833/
https://www.ncbi.nlm.nih.gov/pubmed/28638078
http://dx.doi.org/10.1038/s41598-017-04256-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5479833/
https://www.ncbi.nlm.nih.gov/pubmed/28638078
http://dx.doi.org/10.1038/s41598-017-04256-w

Ejemplares similares