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Sensitivity of human pluripotent stem cells to insulin precipitation induced by peristaltic pump-based medium circulation: considerations on process development

Controlled large-scale production of human pluripotent stem cells (hPSCs) is indispensable for their envisioned clinical translation. Aiming at advanced process development in suspension culture, the sensitivity of hPSC media to continuous peristaltic pump-based circulation, a well-established techn...

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Detalles Bibliográficos
Autores principales: Massai, Diana, Bolesani, Emiliano, Diaz, Diana Robles, Kropp, Christina, Kempf, Henning, Halloin, Caroline, Martin, Ulrich, Braniste, Tudor, Isu, Giuseppe, Harms, Vanessa, Morbiducci, Umberto, Dräger, Gerald, Zweigerdt, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5479836/
https://www.ncbi.nlm.nih.gov/pubmed/28638147
http://dx.doi.org/10.1038/s41598-017-04158-x