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Conformational plasticity and evolutionary analysis of the myotilin tandem Ig domains
Myotilin is a component of the sarcomere where it plays an important role in organisation and maintenance of Z-disk integrity. This involves direct binding to F-actin and filamin C, a function mediated by its Ig domain pair. While the structures of these two individual domains are known, information...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5479843/ https://www.ncbi.nlm.nih.gov/pubmed/28638118 http://dx.doi.org/10.1038/s41598-017-03323-6 |