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Development of lysosome-mimicking vesicles to study the effect of abnormal accumulation of sphingosine on membrane properties

Synthetic systems are widely used to unveil the molecular mechanisms of complex cellular events. Artificial membranes are key examples of models employed to address lipid-lipid and lipid-protein interactions. In this work, we developed a new synthetic system that more closely resembles the lysosome...

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Detalles Bibliográficos
Autores principales: Carreira, Ana C., de Almeida, Rodrigo F. M., Silva, Liana C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5479847/
https://www.ncbi.nlm.nih.gov/pubmed/28638081
http://dx.doi.org/10.1038/s41598-017-04125-6