Immune regulation by oral tolerance induces alternate activation of macrophages and reduces markers of plaque destabilization in Apob(tm2Sgy)/Ldlr(tm1Her/J) mice

Atherosclerosis is the leading cause for cardiovascular mortality. We determined the effect of multi-antigenic construct expressing three peptides AHC (ApoB100, HSP60 and outer membrane protein of chlamydia pneumonia) in stabilizing advanced atherosclerosis in Apob(tm2Sgy)/Ldlr(tm1Her/J) mice. Ather...

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Detalles Bibliográficos
Autores principales: Thota, Lakshmi Narasimha, Ponnusamy, Thiruvelselvan, Philip, Sheena, Lu, Xinjie, Mundkur, Lakshmi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5479867/
https://www.ncbi.nlm.nih.gov/pubmed/28638138
http://dx.doi.org/10.1038/s41598-017-04183-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5479867/
https://www.ncbi.nlm.nih.gov/pubmed/28638138
http://dx.doi.org/10.1038/s41598-017-04183-w

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