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RelB(+) Steady-State Migratory Dendritic Cells Control the Peripheral Pool of the Natural Foxp3(+) Regulatory T Cells

Thymus-derived natural Foxp3(+) CD4(+) regulatory T cells (nTregs) play a key role in maintaining immune tolerance and preventing autoimmune disease. Several studies indicate that dendritic cells (DCs) are critically involved in the maintenance and proliferation of nTregs. However, the mechanisms ho...

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Detalles Bibliográficos
Autores principales: Döhler, Anja, Schneider, Theresa, Eckert, Ina, Ribechini, Eliana, Andreas, Nico, Riemann, Marc, Reizis, Boris, Weih, Falk, Lutz, Manfred B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5479892/
https://www.ncbi.nlm.nih.gov/pubmed/28690613
http://dx.doi.org/10.3389/fimmu.2017.00726