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Endothelial NLRP3 inflammasome activation and arterial neointima formation associated with acid sphingomyelinase during hypercholesterolemia

The NLRP3 inflammasome has been reported to be activated by atherogenic factors, whereby endothelial injury and consequent atherosclerotic lesions are triggered in the arterial wall. However, the mechanisms activating and regulating NLRP3 inflammasomes remain poorly understood. The present study tes...

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Detalles Bibliográficos
Autores principales: Koka, Saisudha, Xia, Min, Chen, Yang, Bhat, Owais M., Yuan, Xinxu, Boini, Krishna M., Li, Pin-Lan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5479959/
https://www.ncbi.nlm.nih.gov/pubmed/28633109
http://dx.doi.org/10.1016/j.redox.2017.06.004