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Endothelial NLRP3 inflammasome activation and arterial neointima formation associated with acid sphingomyelinase during hypercholesterolemia
The NLRP3 inflammasome has been reported to be activated by atherogenic factors, whereby endothelial injury and consequent atherosclerotic lesions are triggered in the arterial wall. However, the mechanisms activating and regulating NLRP3 inflammasomes remain poorly understood. The present study tes...
Autores principales: | Koka, Saisudha, Xia, Min, Chen, Yang, Bhat, Owais M., Yuan, Xinxu, Boini, Krishna M., Li, Pin-Lan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5479959/ https://www.ncbi.nlm.nih.gov/pubmed/28633109 http://dx.doi.org/10.1016/j.redox.2017.06.004 |
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