Activation of p47phox as a Mechanism of Bupivacaine-Induced Burst Production of Reactive Oxygen Species and Neural Toxicity

Bupivacaine has been shown to induce neurotoxicity through inducing excessive reactive oxygen species (ROS), but the underlying mechanism remains unclear. NOX2 is one of the most important sources of ROS in the nervous system, and its activation requires the membrane translocation of subunit p47phox...

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Detalles Bibliográficos
Autores principales: Li, Yu-jie, Zhao, Wei, Yu, Xu-jiao, Li, Feng-xian, Liu, Zi-ting, Li, Le, Xu, Shi-yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5480047/
https://www.ncbi.nlm.nih.gov/pubmed/28751934
http://dx.doi.org/10.1155/2017/8539026

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5480047/
https://www.ncbi.nlm.nih.gov/pubmed/28751934
http://dx.doi.org/10.1155/2017/8539026

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