Effects of SMYD2‐mediated EML4‐ALK methylation on the signaling pathway and growth in non‐small‐cell lung cancer cells

A specific subtype of non‐small‐cell lung cancer (NSCLC) characterized with an EML4‐ALK fusion gene, which drives constitutive oncogenic activation of anaplastic lymphoma kinase (ALK), shows a good clinical response to ALK inhibitors. We have reported multiple examples implying the biological signif...

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Detalles Bibliográficos
Autores principales: Wang, Rui, Deng, Xiaolan, Yoshioka, Yuichiro, Vougiouklakis, Theodore, Park, Jae‐Hyun, Suzuki, Takehiro, Dohmae, Naoshi, Ueda, Koji, Hamamoto, Ryuji, Nakamura, Yusuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5480063/
https://www.ncbi.nlm.nih.gov/pubmed/28370702
http://dx.doi.org/10.1111/cas.13245

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5480063/
https://www.ncbi.nlm.nih.gov/pubmed/28370702
http://dx.doi.org/10.1111/cas.13245

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