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HSP90 inhibitor AUY922 can reverse Fulvestrant induced feedback reaction in human breast cancer cells

Hormone therapy has become one of the main strategies for breast cancer, however, many estrogen receptor (ER) positive patients end in tumor collapse due to initial or acquired resistance to hormone treatment, which includes Fulvestrant. Here we report that ErbB receptors and downstream PI3K/AKT and...

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Detalles Bibliográficos
Autores principales: Bai, Jingchao, Zhou, Guanglin, Qiu, Yufan, Hu, Yunhui, Liu, Jingjing, Zhao, Jing, Zhang, Sheng, Zhang, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5480065/
https://www.ncbi.nlm.nih.gov/pubmed/28301080
http://dx.doi.org/10.1111/cas.13238