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Downregulation of Talin1 promotes hepatocellular carcinoma progression through activation of the ERK1/2 pathway
Talin1 is an adaptor protein that conjugates integrins to the cytoskeleton and regulates integrins and focal adhesion signaling. Several studies have found that Talin1 is overexpressed in several tumor types and promotes tumor progression. However, the explicit role of Talin1 in hepatocellular carci...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5480078/ https://www.ncbi.nlm.nih.gov/pubmed/28375585 http://dx.doi.org/10.1111/cas.13247 |