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BRAF mutations are associated with increased iron regulatory protein‐2 expression in colorectal tumorigenesis

A role for iron in carcinogenesis is supported by evidence that iron metabolism proteins are modulated in cancer progression. To date, however, the expression of iron regulatory protein‐2 (IRP2), which is known to regulate several iron metabolism proteins, has not been assessed in colorectal cancer....

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Detalles Bibliográficos
Autores principales: Horniblow, Richard D., Bedford, Matthew, Hollingworth, Robert, Evans, Sarah, Sutton, Emily, Lal, Neeraj, Beggs, Andrew, Iqbal, Tariq H., Tselepis, Chris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5480081/
https://www.ncbi.nlm.nih.gov/pubmed/28281325
http://dx.doi.org/10.1111/cas.13234