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Current guidelines for BRCA testing of breast cancer patients are insufficient to detect all mutation carriers

BACKGROUND: Identification of BRCA mutations in breast cancer (BC) patients influences treatment and survival and may be of importance for their relatives. Testing is often restricted to women fulfilling high-risk criteria. However, there is limited knowledge of the sensitivity of such a strategy, a...

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Detalles Bibliográficos
Autores principales: Grindedal, Eli Marie, Heramb, Cecilie, Karsrud, Inga, Ariansen, Sarah Louise, Mæhle, Lovise, Undlien, Dag Erik, Norum, Jan, Schlichting, Ellen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5480128/
https://www.ncbi.nlm.nih.gov/pubmed/28637432
http://dx.doi.org/10.1186/s12885-017-3422-2