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Hierarchical cortical transcriptome disorganization in autism

BACKGROUND: Autism spectrum disorders (ASD) are etiologically heterogeneous and complex. Functional genomics work has begun to identify a diverse array of dysregulated transcriptomic programs (e.g., synaptic, immune, cell cycle, DNA damage, WNT signaling, cortical patterning and differentiation) pot...

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Detalles Bibliográficos
Autores principales: Lombardo, Michael V., Courchesne, Eric, Lewis, Nathan E., Pramparo, Tiziano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5480153/
https://www.ncbi.nlm.nih.gov/pubmed/28649314
http://dx.doi.org/10.1186/s13229-017-0147-7