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Downregulation of Talin-1 expression associates with increased proliferation and migration of vascular smooth muscle cells in aortic dissection

BACKGROUND: This study aimed to assessed whether Talin-1 is involved in the pathogenesis of aortic dissection via regulating vascular smooth muscle cell (VSMC) biological function. METHODS: Human aortic samples were obtained from organ donors who died from nonvascular diseases as normal controls and...

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Detalles Bibliográficos
Autores principales: Wei, Xiaolong, Sun, Yudong, Wu, Yani, Zhu, Jiang, Gao, Bin, Yan, Han, Zhao, Zhiqing, Zhou, Jian, Jing, Zaiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5480185/
https://www.ncbi.nlm.nih.gov/pubmed/28637452
http://dx.doi.org/10.1186/s12872-017-0588-0