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The role of JAK-STAT signaling pathway and its regulators in the fate of T helper cells

The Janus kinase (JAK)-signal transducer and activator of transcription (STAT) pathway plays critical roles in orchestrating of immune system, especially cytokine receptors and they can modulate the polarization of T helper cells. This pathway is regulated by an array of regulator proteins, includin...

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Detalles Bibliográficos
Autores principales: Seif, Farhad, Khoshmirsafa, Majid, Aazami, Hossein, Mohsenzadegan, Monireh, Sedighi, Gholamreza, Bahar, Mohammadali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5480189/
https://www.ncbi.nlm.nih.gov/pubmed/28637459
http://dx.doi.org/10.1186/s12964-017-0177-y