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MiR21 sensitized B-lymphoma cells to ABT-199 via ICOS/ICOSL-mediated interaction of Treg cells with endothelial cells

BACKGROUND: MicroRNAs (miRs) are involved in tumor progression by regulating tumor cells and tumor microenvironment. MiR21 is overexpressed in diffuse large B-cell lymphoma (DLBCL) and its biological impact on tumor microenvironment remains unclear. METHODS: MiR21 was assessed by quantitative RT-PCR...

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Detalles Bibliográficos
Autores principales: Zheng, Zhong, Xu, Peng-Peng, Wang, Li, Zhao, Hui-Jin, Weng, Xiang-Qin, Zhong, Hui-Juan, Qu, Bin, Xiong, Jie, Zhao, Yan, Wang, Xue-Feng, Janin, Anne, Zhao, Wei-Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5480196/
https://www.ncbi.nlm.nih.gov/pubmed/28637496
http://dx.doi.org/10.1186/s13046-017-0551-z