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MicroRNA-200c and microRNA- 141 are regulated by a FOXP3-KAT2B axis and associated with tumor metastasis in breast cancer

BACKGROUND: Members of the microRNA (miR)-200 family, which are involved in tumor metastasis, have potential as cancer biomarkers, but their regulatory mechanisms remain elusive. METHODS: We investigated FOXP3-inducible breast cancer cells, Foxp3 heterozygous Scurfy mutant (Foxp3 (sf/+)) female mice...

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Detalles Bibliográficos
Autores principales: Zhang, Guangxin, Zhang, Wei, Li, Bingjin, Stringer-Reasor, Erica, Chu, Chengjing, Sun, Liyan, Bae, Sejong, Chen, Dongquan, Wei, Shi, Jiao, Kenneth, Yang, Wei-Hsiung, Cui, Ranji, Liu, Runhua, Wang, Lizhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5480201/
https://www.ncbi.nlm.nih.gov/pubmed/28637482
http://dx.doi.org/10.1186/s13058-017-0858-x