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Total syntheses of the archazolids: an emerging class of novel anticancer drugs

V-ATPase has recently emerged as a promising novel anticancer target based on extensive in vitro and in vivo studies with the archazolids, complex polyketide macrolides which present the most potent V-ATPase inhibitors known to date, rendering these macrolides important lead structures for the devel...

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Detalles Bibliográficos
Autores principales: Scheeff, Stephan, Menche, Dirk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5480361/
https://www.ncbi.nlm.nih.gov/pubmed/28684988
http://dx.doi.org/10.3762/bjoc.13.108