Cargando…
Total syntheses of the archazolids: an emerging class of novel anticancer drugs
V-ATPase has recently emerged as a promising novel anticancer target based on extensive in vitro and in vivo studies with the archazolids, complex polyketide macrolides which present the most potent V-ATPase inhibitors known to date, rendering these macrolides important lead structures for the devel...
Autores principales: | Scheeff, Stephan, Menche, Dirk |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Beilstein-Institut
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5480361/ https://www.ncbi.nlm.nih.gov/pubmed/28684988 http://dx.doi.org/10.3762/bjoc.13.108 |
Ejemplares similares
-
Design, Synthesis and Biological Evaluation of Highly Potent Simplified Archazolids
por: Rivière, Solenne, et al.
Publicado: (2020) -
Anti-leukemic effects of the V-ATPase inhibitor Archazolid A
por: Zhang, Siwei, et al.
Publicado: (2015) -
The vacuolar-type ATPase inhibitor archazolid increases tumor cell adhesion to endothelial cells by accumulating extracellular collagen
por: Luong, Betty, et al.
Publicado: (2018) -
Archazolid and apicularen: Novel specific V-ATPase inhibitors
por: Huss, Markus, et al.
Publicado: (2005) -
Suzuki coupling-based synthesis of VATPase inhibitor archazolid natural product derived fragments
por: Vincent, Cooper T., et al.
Publicado: (2019)