High-Throughput Patch Clamp Screening in Human α6-Containing Nicotinic Acetylcholine Receptors

Nicotine, the addictive component of tobacco products, is an agonist at nicotinic acetylcholine receptors (nAChRs) in the brain. The subtypes of nAChR are defined by their α- and β-subunit composition. The α6β2β3 nAChR subtype is expressed in terminals of dopaminergic neurons that project to the nuc...

Descripción completa

Detalles Bibliográficos
Autores principales: Armstrong, Lucas C., Kirsch, Glenn E., Fedorov, Nikolai B., Wu, Caiyun, Kuryshev, Yuri A., Sewell, Abby L., Liu, Zhiqi, Motter, Arianne L., Leggett, Carmine S., Orr, Michael S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5480602/
https://www.ncbi.nlm.nih.gov/pubmed/28298165
http://dx.doi.org/10.1177/2472555217696794

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5480602/
https://www.ncbi.nlm.nih.gov/pubmed/28298165
http://dx.doi.org/10.1177/2472555217696794

Ejemplares similares