Ribosomal DNA copy number loss and sequence variation in cancer

Ribosomal DNA is one of the most variable regions in the human genome with respect to copy number. Despite the importance of rDNA for cellular function, we know virtually nothing about what governs its copy number, stability, and sequence in the mammalian genome due to challenges associated with map...

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Detalles Bibliográficos
Autores principales: Xu, Baoshan, Li, Hua, Perry, John M., Singh, Vijay Pratap, Unruh, Jay, Yu, Zulin, Zakari, Musinu, McDowell, William, Li, Linheng, Gerton, Jennifer L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5480814/
https://www.ncbi.nlm.nih.gov/pubmed/28640831
http://dx.doi.org/10.1371/journal.pgen.1006771

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5480814/
https://www.ncbi.nlm.nih.gov/pubmed/28640831
http://dx.doi.org/10.1371/journal.pgen.1006771

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