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Inhibition of NF-κB improves the stress resistance and myogenic differentiation of MDSPCs isolated from naturally aged mice

A decline in the regenerative capacity of adult stem cells with aging is well documented. As a result of this decline, the efficacy of autologous stem cell therapies is likely to decline with increasing donor age. In these cases, strategies to restore the function of aged stem cells would have clini...

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Detalles Bibliográficos
Autores principales: Proto, Jonathan D., Lu, Aiping, Dorronsoro, Akaitz, Scibetta, Alex, Robbins, Paul D., Niedernhofer, Laura J., Huard, Johnny
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5480862/
https://www.ncbi.nlm.nih.gov/pubmed/28640861
http://dx.doi.org/10.1371/journal.pone.0179270