Cargando…

Inhibition of NF-κB improves the stress resistance and myogenic differentiation of MDSPCs isolated from naturally aged mice

A decline in the regenerative capacity of adult stem cells with aging is well documented. As a result of this decline, the efficacy of autologous stem cell therapies is likely to decline with increasing donor age. In these cases, strategies to restore the function of aged stem cells would have clini...

Descripción completa

Detalles Bibliográficos
Autores principales:	Proto, Jonathan D., Lu, Aiping, Dorronsoro, Akaitz, Scibetta, Alex, Robbins, Paul D., Niedernhofer, Laura J., Huard, Johnny
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5480862/ https://www.ncbi.nlm.nih.gov/pubmed/28640861 http://dx.doi.org/10.1371/journal.pone.0179270

Ejemplares similares

Regenerating the injured kidney with human umbilical cord mesenchymal stem cell-derived exosomes
por: Dorronsoro, Akaitz, et al.
Publicado: (2013)

ATM is a key driver of NF-κB-dependent DNA-damage-induced senescence, stem cell dysfunction and aging
por: Zhao, Jing, et al.
Publicado: (2020)

Partial Ablation of Non-Myogenic Progenitor Cells as a Therapeutic Approach to Duchenne Muscular Dystrophy
por: Gao, Zhanguo, et al.
Publicado: (2021)

Development of novel NEMO-binding domain mimetics for inhibiting IKK/NF-κB activation
por: Zhao, Jing, et al.
Publicado: (2018)

Novel small molecule inhibition of IKK/NF‐κB activation reduces markers of senescence and improves healthspan in mouse models of aging
por: Zhang, Lei, et al.
Publicado: (2021)

IL1β Induces Mesenchymal Stem Cells Migration and Leucocyte Chemotaxis Through NF-κB
por: Carrero, Rubén, et al.
Publicado: (2012)

MyoD-dependent regulation of NF-κB activity couples cell-cycle withdrawal to myogenic differentiation
por: Parker, Maura H, et al.
Publicado: (2012)

NF-κB inhibition reveals a novel role for HGF during skeletal muscle repair
por: Proto, J D, et al.
Publicado: (2015)

Retraction: MyoD-dependent regulation of NF-κB activity couples cell-cycle withdrawal to myogenic differentiation
por: Parker, Maura H, et al.
Publicado: (2013)

Mesenchymal stem cell‐derived extracellular vesicles reduce senescence and extend health span in mouse models of aging
por: Dorronsoro, Akaitz, et al.
Publicado: (2021)

Genetic signature of human longevity in PKC and NF‐κB signaling
por: Ryu, Seungjin, et al.
Publicado: (2021)

Murine and Human Myogenic Cells Identified by Elevated Aldehyde Dehydrogenase Activity: Implications for Muscle Regeneration and Repair
por: Vella, Joseph B., et al.
Publicado: (2011)

Stimulation of Non-canonical NF-κB Through Lymphotoxin-β-Receptor Impairs Myogenic Differentiation and Regeneration of Skeletal Muscle
por: Schmidt, Manuel, et al.
Publicado: (2021)

Muscle-derived stem/progenitor cell dysfunction limits healthspan and lifespan in a murine progeria model
por: Lavasani, Mitra, et al.
Publicado: (2012)

Pharmacologic IKK/NF-κB inhibition causes antigen presenting cells to undergo TNFα dependent ROS-mediated programmed cell death
por: Tilstra, Jeremy S., et al.
Publicado: (2014)

Expansion of myeloid‐derived suppressor cells with aging in the bone marrow of mice through a NF‐κB‐dependent mechanism
por: Flores, Rafael R., et al.
Publicado: (2017)

mTOR signaling plays a critical role in the defects observed in muscle‐derived stem/progenitor cells isolated from a murine model of accelerated aging
por: Takayama, Koji, et al.
Publicado: (2016)

Influences of donor and host age on human muscle-derived stem cell-mediated bone regeneration
por: Gao, Xueqin, et al.
Publicado: (2018)

Rapamycin Rescues Age-Related Changes in Muscle-Derived Stem/Progenitor Cells from Progeroid Mice
por: Kawakami, Yohei, et al.
Publicado: (2019)

Regulation of human bone marrow stromal cell proliferation and differentiation capacity by glucocorticoid receptor and AP-1 crosstalk
por: Cárcamo-Orive, Iván, et al.
Publicado: (2010)

Natural chalcones as dual inhibitors of HDACs and NF-κB
por: ORLIKOVA, B., et al.
Publicado: (2012)

A transcriptomic study of myogenic differentiation under the overexpression of PPARγ by RNA-Seq
por: He, Kan, et al.
Publicado: (2017)

Characterization of the Methylation Status of Pax7 and Myogenic Regulator Factors in Cell Myogenic Differentiation
por: Chao, Zhe, et al.
Publicado: (2016)

Carbon metabolism-mediated myogenic differentiation
por: Bracha, Abigail L., et al.
Publicado: (2010)

JAK-STAT pathway and myogenic differentiation
por: Jang, You-Na, et al.
Publicado: (2013)

Gene amplification during myogenic differentiation
por: Fischer, Ulrike, et al.
Publicado: (2016)

Modeling Stem Cell Myogenic Differentiation
por: Deshpande, Rajiv S., et al.
Publicado: (2017)

Reductive stress impairs myogenic differentiation
por: Rajasekaran, Namakkal S., et al.
Publicado: (2020)

Improvement of Cartilage Repair With Biologically Regulated Marrow Stimulation by Blocking TGF-β1 in A Rabbit Osteochondral Defect Model
por: Utsunomiya, Hajime, et al.
Publicado: (2019)

The beneficial effect of intra-articular injection of losartan on the microfracture mediated cartilage repair is dose dependent
por: Gao, Xueqin, et al.
Publicado: (2021)

Poster 247: Muscle ERRγ Overexpression Mitigates the Muscle Atrophy after ACL injury
por: Huard, Johnny, et al.
Publicado: (2022)

NF-κB, Mesenchymal Differentiation and Glioblastoma
por: Yamini, Bakhtiar
Publicado: (2018)

EV-mediated promotion of myogenic differentiation is dependent on dose, collection medium, and isolation method
por: Hanson, Britt, et al.
Publicado: (2023)

Reporter-Based Isolation of Developmental Myogenic Progenitors
por: Kheir, Eyemen, et al.
Publicado: (2018)

Natural antisense RNA Foxk1-AS promotes myogenic differentiation by inhibiting Foxk1 activity
por: Li, Chun, et al.
Publicado: (2022)

Identification of the NF-κB inhibitor A20 as a key regulator for human adipogenesis
por: Dorronsoro, A, et al.
Publicado: (2013)

MITOSIS AND THE PROCESSES OF DIFFERENTIATION OF MYOGENIC CELLS IN VITRO
por: Bischoff, Richard, et al.
Publicado: (1969)

Arsenic Inhibits Myogenic Differentiation and Muscle Regeneration
por: Yen, Yuan-Peng, et al.
Publicado: (2010)

Confined Sandwichlike Microenvironments Tune Myogenic Differentiation
por: Ballester-Beltrán, José, et al.
Publicado: (2017)

Caspase-3, myogenic transcription factors and cell cycle inhibitors are regulated by leukemia inhibitory factor to mediate inhibition of myogenic differentiation
por: Hunt, Liam C, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_b0ioiek8oviefurer8j5371pa0