Ligand-mediated and tertiary interactions cooperatively stabilize the P1 region in the guanine-sensing riboswitch

Riboswitches are genetic regulatory elements that control gene expression depending on ligand binding. The guanine-sensing riboswitch (Gsw) binds ligands at a three-way junction formed by paired regions P1, P2, and P3. Loops L2 and L3 cap the P2 and P3 helices and form tertiary interactions. Part of...

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Detalles Bibliográficos
Autores principales: Hanke, Christian A., Gohlke, Holger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5480868/
https://www.ncbi.nlm.nih.gov/pubmed/28640851
http://dx.doi.org/10.1371/journal.pone.0179271

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5480868/
https://www.ncbi.nlm.nih.gov/pubmed/28640851
http://dx.doi.org/10.1371/journal.pone.0179271

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