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Ligand-mediated and tertiary interactions cooperatively stabilize the P1 region in the guanine-sensing riboswitch
Riboswitches are genetic regulatory elements that control gene expression depending on ligand binding. The guanine-sensing riboswitch (Gsw) binds ligands at a three-way junction formed by paired regions P1, P2, and P3. Loops L2 and L3 cap the P2 and P3 helices and form tertiary interactions. Part of...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5480868/ https://www.ncbi.nlm.nih.gov/pubmed/28640851 http://dx.doi.org/10.1371/journal.pone.0179271 |