Next generation sequencing of the clonal IGH rearrangement detects ongoing mutations and interfollicular trafficking in in situ follicular neoplasia

Follicular lymphoma (FL) is characterized genetically by a significant intraclonal diversity of rearranged immunoglobulin heavy chain (IGH) genes and a substantial cell migration activity (follicular trafficking). Recently, in situ follicular neoplasia (ISFN), characterized by accumulations of immun...

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Detalles Bibliográficos
Autores principales: Kosmidis, Perikles, Bonzheim, Irina, Dufke, Claudia, Colak, Sema, Hentrich, Thomas, Schroeder, Christopher, Bauer, Peter, Adam, Patrick, Fend, Falko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5480878/
https://www.ncbi.nlm.nih.gov/pubmed/28640838
http://dx.doi.org/10.1371/journal.pone.0178503

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5480878/
https://www.ncbi.nlm.nih.gov/pubmed/28640838
http://dx.doi.org/10.1371/journal.pone.0178503

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