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Next generation sequencing of the clonal IGH rearrangement detects ongoing mutations and interfollicular trafficking in in situ follicular neoplasia
Follicular lymphoma (FL) is characterized genetically by a significant intraclonal diversity of rearranged immunoglobulin heavy chain (IGH) genes and a substantial cell migration activity (follicular trafficking). Recently, in situ follicular neoplasia (ISFN), characterized by accumulations of immun...
Autores principales: | Kosmidis, Perikles, Bonzheim, Irina, Dufke, Claudia, Colak, Sema, Hentrich, Thomas, Schroeder, Christopher, Bauer, Peter, Adam, Patrick, Fend, Falko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5480878/ https://www.ncbi.nlm.nih.gov/pubmed/28640838 http://dx.doi.org/10.1371/journal.pone.0178503 |
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